偶也做点贡献吧,关于试管婴儿的成功率 [复制链接]

引自http://www.cdc.gov/reproductivehealth/ART02/sect2_fig3-13.htm#f6 2002年全美的试管婴儿案例

本人不是专业人士,翻译难免不准,大家凑和看吧

结论:

样本:

• 85,826 cycles started 启动的周期数
  
  
  
  
• 74,519 retrievals 重复的周期数 retrievals可能翻译的不准,可能指的是实际取到卵的情况
  
  
  
  
• 69,857 transfers 移植数
  
  
  
  
• 29,423 pregnancies 怀孕数
  
  
  
  
• 24,324 live-birth deliveries 生产数

中断周期的原因

使用新鲜卵子或囊胚的成功率

• Pregnancies per cycle 34.3% 每周期怀孕率 haha还是很高的
• Live births per cycle 28.3% 每周期生产率
• Live births per retrieval 32.6% 重做的生产率 ?不太明白
• Live births per transfer 34.8% 每次移植的生产率
• Singleton live births per cycle 21.1% 每周期的单胎生产
• Singleton live births per transfer 22.5% 每次移植的单台生产

怀孕的情况

生产情况:

• 82.7% 怀孕并成功生产
  • 单胎53.7%
  • 多胎29.0%
• 16.4% 怀孕没有成功:
  • 流产15.0%
  • 减胎 0.9%
  • Stillbirths 0.5% 生下死婴

女方年龄分布情况

• Age 22, 0.16%
• Age 23, 0.29%
• Age 24, 0.51%
• Age 25, 0.82%
• Age 26, 1.32%
• Age 27, 1.87%
• Age 28, 2.71%
• Age 29, 3.68%
• Age 30, 5.02%
• Age 31, 6.23%
• Age 32, 6.74%
• Age 33, 7.24%
• Age 34, 7.23%
• Age 35, 7.72%
• Age 36, 7.28%
• Age 37, 7.34%
• Age 38, 7.33%
• Age 39, 7.11%
• Age 40, 5.96%
• Age 41, 5.07%
• Age 42, 3.97%
• Age 43, 2.44%
• Age 44, 1.25%
• Age 45, 0.52%
• Age 46, 0.20%

不同年龄的成功率

年龄 怀孕率 生产率 单胎生产率

• Age 22, Pregnancy rate 38.3%, Live birth rate 33.1%, Singleton live birth rate 25.6%
• Age 23, Pregnancy rate 47.1%, Live birth rate 38.9%, Singleton live birth rate 26.2%
• Age 24, Pregnancy rate 44.8%, Live birth rate 39.5%, Singleton live birth rate 25.5%
• Age 25, Pregnancy rate 43.1%, Live birth rate 37.5%, Singleton live birth rate 24.2%
• Age 26, Pregnancy rate 42.9%, Live birth rate 38.4%, Singleton live birth rate 23.4%
• Age 27, Pregnancy rate 45.8%, Live birth rate 40.1%, Singleton live birth rate 23.2%
• Age 28, Pregnancy rate 42.9%, Live birth rate 37.5%, Singleton live birth rate 22.0%
• Age 29, Pregnancy rate 45.5%, Live birth rate 39.6%, Singleton live birth rate 23.8%
• Age 30, Pregnancy rate 42.3%, Live birth rate 36.8%, Singleton live birth rate 22.0%
• Age 31, Pregnancy rate 44.2%, Live birth rate 38.4%, Singleton live birth rate 22.7%
• Age 32, Pregnancy rate 43.0%, Live birth rate 37.5%, Singleton live birth rate 23.6%
• Age 33, Pregnancy rate 41.3%, Live birth rate 35.8%, Singleton live birth rate 22.4%
• Age 34, Pregnancy rate 39.3%, Live birth rate 33.5%, Singleton live birth rate 20.8%
• Age 35, Pregnancy rate 38.2%, Live birth rate 32.6%, Singleton live birth rate 20.8%
• Age 36, Pregnancy rate 37.4%, Live birth rate 31.1%, Singleton live birth rate 19.6%
• Age 37, Pregnancy rate 33.7%, Live birth rate 28.2%, Singleton live birth rate 18.9%
• Age 38, Pregnancy rate 31.7%, Live birth rate 24.9%, Singleton live birth rate 17.2%
• Age 39, Pregnancy rate 26.9%, Live birth rate 19.9%, Singleton live birth rate 14.9%
• Age 40, Pregnancy rate 23.0%, Live birth rate 16.1%, Singleton live birth rate 12.6%
• Age 41, Pregnancy rate 18.7%, Live birth rate 12.1%, Singleton live birth rate 9.7%
• Age 42, Pregnancy rate 15.4%, Live birth rate 9.0%, Singleton live birth rate 7.5%
• Age 43, Pregnancy rate 11.5%, Live birth rate 6.3%, Singleton live birth rate 6.0%
• Age 44, Pregnancy rate 6.7%, Live birth rate 2.6%, Singleton live birth rate 2.4%
• Age 45, Pregnancy rate 2.9%, Live birth rate 1.1%, Singleton live birth rate 0.9%
• Age 46, Pregnancy rate 2.9%, Live birth rate 0.6%, Singleton live birth rate 0.6%

40岁以上妇女的成功率

• Age 40, Pregnancy rate 23.0%, Live birth rate 16.1%, Singleton live birth rate 12.6%
• Age 41, Pregnancy rate 18.7%, Live birth rate 12.1%, Singleton live birth rate 9.7%
• Age 42, Pregnancy rate 15.4%, Live birth rate 9.0%, Singleton live birth rate 7.5%
• Age 43, Pregnancy rate 11.5%, Live birth rate 6.3 %, Singleton live birth rate 6.0%
• >Age 43, Pregnancy rate 5.2%, Live birth rate 2.0%, Singleton live birth rate 1.8%

不同年龄的流产情况:

• Age < 25, 13.6%
• Age 25, 13.0%
• Age 26, 10.5%
• Age 27, 12.4%
• Age 28, 12.6%
• Age 29, 13.0%
• Age 30, 13.1%
• Age 31, 13.1%
• Age 32, 12.6%
• Age 33, 13.3%
• Age 34, 14.7%
• Age 35, 14.7%
• Age 36, 16.8%
• Age 37, 16.2%
• Age 38, 21.6%
• Age 39, 26.2%
• Age 40, 30.2%
• Age 41, 35.3%
• Age 42, 41.8%
• Age 43, 45.0%
• Age 44, 61.1%
• Age >44, 64.0%

按年龄段统计

年龄段 重复多次 移植 怀孕 生产

• <Age 35, Retrieval 91%, Transfer 86%, Pregnancy 43%, Live birth 37%
• Age 35–37, Retrieval 87%, Transfer 83%, Pregnancy 36%, Live birth 31%
• Age 38–40, Retrieval 83%, Transfer 78%, Pregnancy 28%, Live birth 21%
• Age 41–42, Retrieval 80%, Transfer 73%, Pregnancy 17%, Live birth 11%
• >Age 42, Retrieval 76%, Transfer 65%, Pregnancy 9%, Live birth 4%